Jewel wasp (Ampulex compressa),

Female wasps of this species were reported to sting a cockroach (specifically a Periplaneta americana, Periplaneta australasiae, or Nauphoeta rhombifolia)[2] twice, delivering venom. Researchers[7] using radioactive labeling demonstrated that the wasp stings precisely into specific ganglia of the roach. It delivers an initial sting to a thoracic ganglion and injects venom to mildly and reversibly paralyze the front legs of its victim. A biochemically-induced transient paralysis takes over the cockroach,[8] where the temporary loss of mobility facilitates the second venomous sting at a precise spot in the victim's head ganglia (brain), in the section that controls the escape reflex. As a result of this sting, the roach will first groom extensively, and then become sluggish and fail to show normal escape responses.[9] The venom is reported to block receptors for the neurotransmitter octopamine.[10]

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