2. Snakeroot extract
Snakeroot (Ageratina pichinchensis) extract is an antifungal made from plants in the sunflower family.
A 2008 studyTrusted Source showed that the remedy is as effective against toenail fungus as the prescription antifungal medicine ciclopirox.
For the study, snakeroot extract was applied to the affected area every third day for the first month, twice a week for the second month, and once a week for the third month.